JIST

Abstract

In this study, a histopathological examination of lungs, liver and kidneys in aluminium phosphide poisoning cases was done, and demonstrated significant pathological features in the form of fatty infiltration and hepatocyte necrosis in the liver, tubular necrosis in the kidneys with intra-tubular haemorrhages in a few cases, and pulmonary oedema, alveolar septal thickening, intra-alveolar haemorrhages and disruption of inter-alveolar septa in the lungs.

On correlating these histopathological features in the tissues with the survival period of the cases, it was observed that the liver was affected among only those cases surviving for more than 24 hrs following the intake of aluminium phosphide, while features of pathology in the lungs and kidneys were noted in general among all the cases.