JIST

Abstract

Background: Neuroleptic Malignant Syndrome is a life-threatening neuropsychiatric emergency because of the use of neuroleptic drugs characterized by specifically clinical syndrome, like changes in mental status, stiffness, fever, and dysautonomia. The current problem in managing of the Neuroleptic Malignant Syndrome is still not yet optimized causing the death rate is quite high with an incidence rate of the Neuroleptic Malignant Syndrome is ranging from 0.02 to 3 percent among patients taking antipsychotic agents occur throughout the world.

Methods: From published articles conducted by the experts that concerning in neuroleptic malignant syndromes and its management have been considered and reviewed.

Comments: It is important for medical workers to understand steps in managing and treating Neuroleptic Malignant Syndrome from the initial management such as the immediate termination of Neuroleptic Malignant Syndrome drug agents, giving supportive management, early detection of clinical symptoms, prevention of risk factors until understanding the medical conditions associated with Neuroleptic Malignant Syndrome specifically.