JIST

Abstract

Organophosphate induced delayed polyneuropathy is a rare clinical manifestation resulting from exposure to certain organophosphorus esters.[1] It is characterized by degeneration of both peripheral and central nervous system axons occurring 1-4 weeks after a single or short term exposure.[2] This syndrome is due to inhibition of neuropathy target esterase (NTE). It usually starts with cramping muscle pain in both lower limbs, distal numbness and paresthesia, followed by progressive weakness which may become irreversible.[2] Decreased or absent deep tendon reflexes both the lower limb is usually seen, rarely even upper limbs may be affected.[3] We report a  rare case of organophosphorus induced delayed polyneuropathy overlapping with intermediate syndrome with  possible features of non compressive myelopathy.